Synthesis of <i>D</i>-provitamins containing a side-chain isozazoline ring

Authors

  • P. П. Литвиновская Institute of Bioorganic Chemistry, Academy of Sciences of Belarus, 220141 Minsk
  • Н. B. Коваль Institute of Bioorganic Chemistry, Academy of Sciences of Belarus, 220141 Minsk
  • B. А. Хрипач Institute of Bioorganic Chemistry, Academy of Sciences of Belarus, 220141 Minsk

Abstract

This is the first report of the synthesis of 20-isoxazoline steroids containing a 5,7-diene group by 1,3-dipolar cycloaddition of nitrile oxides to Δ22-steroids, leading to 20-isoxazolin-5′-ylsteroids, or of steroidal 22-nitrile oxides to low-molecular-weight dipolarophiles, giving 20-isoxazolin-3′-ylsteroids.

How to Cite
Litvinovskaya, R. P.; Koval', N. V.; Khripach, V. A. Chem. Heterocycl. Compd. 1998, 34, 241. [Khim. Geterotsikl. Soedin. 1998, 34, 267.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02315192

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Published

1998-02-25

Issue

No. 2 (1998)

Section

Original Papers