Synthesis and heterocyclization of osazones of carbonyl-substituted glyoxals

Abstract

Enolates of α-chloro-β-oxoaldehydes react with arylhydrazines in the presence of acetic acid, forming osazones of carbonyl-substituted glyoxals. The same osazones are obtained by the reaction of β-oxo-α-chlorenamines with arylhydrazines. Under conditions of acid catalysis, these osazones undergo intramolecular heterocyclization to the corresponding functionalized pyrazoles.

How to Cite
Guseinov, F. I.; Yudina, N. A.; Klimentova, G. Y. Chem. Heterocycl. Compd. 1998, 34, 167. [Khim. Geterotsikl. Soedin. 1998, 34, 190.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02315178