SYNTHESIS OF 3,13-DICHLOROBENZO[<i>b</i>]QUINO[4,3-<i>h</i>][1,6]NAPHTHYRIDIN-6(5<i>H</i>)-ONE DERIVATIVES FROM 2-OXOQUINOLINE-3-CARBONYL CHLORIDE AND 2,6-DICHLOROQUINOLIN-4-AMINE

Authors

  • Adhiyaman Kottai Munusamy Magesh Selva Kumar DEPARTMENT OF CHEMISTRY, BHARATHIAR UNIVERSITY, COIMBATORE-641046 TAMILNADU
  • Subramanian Parameswaran Rajendran DEPARTMENT OF CHEMISTRY, BHARATHIAR UNIVERSITY, COIMBATORE-641046 TAMILNADU
  • Selvaraj Mohana Roopan School of Advanced Sciences, VIT University, Vellore 632 014, Tamilnadu, India.

DOI:

https://doi.org/10.1007/2068

Keywords:

2-chloroquinoline-3-carbaldehyde, 2, 6-dichloroquinolin-4-amine, N-(quinolin-4-yl)-2-oxo-1, 2-dihydroquinoline-3-carboxamide, benzo[b]quino[4, 3-h][1, 6]naphthyridin-6(5H)-one

Abstract

The reaction of 2-oxo-1,2-dihydroquinoline-3-carbonyl chlorides and 2,6-dichloroquinolin-4-amine leads to the formation of N-(2,6-dichloroquinolin-4-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamides. The latter is cyclized to fused [1,6]naphthyridine derivative – 3,13-dichlorobenzo[b]quino[4,3-h][1,6]naphthyridin-6(5H)-one, under heating in polyphosphoric acid at 150°C. The reaction sequence was generalized and was extended to synthetic derivatives. The structures of all synthesized compounds were confirmed by spectral data and elemental analysis.

How to Cite
Magesh Selva Kumar, A. K. M.; Rajendran, S. P.; Mohana Roopan, S. Chem. Heterocycl. Compd. 2015, 51, 346. [Khim. Geterotsikl. Soedin. 2015, 51, 346.]

For this article in the English edition see DOI 10.1007/s10593-015-1706-5

 

Author Biographies

Adhiyaman Kottai Munusamy Magesh Selva Kumar, DEPARTMENT OF CHEMISTRY, BHARATHIAR UNIVERSITY, COIMBATORE-641046 TAMILNADU

Research Scholar in Department of chemistry

Subramanian Parameswaran Rajendran, DEPARTMENT OF CHEMISTRY, BHARATHIAR UNIVERSITY, COIMBATORE-641046 TAMILNADU

Professor (Rtd) in Department of Chemistry

Selvaraj Mohana Roopan, School of Advanced Sciences, VIT University, Vellore 632 014, Tamilnadu, India.

Assistant Professor in VIT University

Downloads

Published

2015-04-27

Issue

Vol. 51 No. 4 (2015)

Section

Original Papers