SYNTHESIS OF 3,13-DICHLOROBENZO[<i>b</i>]QUINO[4,3-<i>h</i>][1,6]NAPHTHYRIDIN-6(5<i>H</i>)-ONE DERIVATIVES FROM 2-OXOQUINOLINE-3-CARBONYL CHLORIDE AND 2,6-DICHLOROQUINOLIN-4-AMINE

Авторы

  • Adhiyaman Kottai Munusamy Magesh Selva Kumar DEPARTMENT OF CHEMISTRY, BHARATHIAR UNIVERSITY, COIMBATORE-641046 TAMILNADU
  • Subramanian Parameswaran Rajendran DEPARTMENT OF CHEMISTRY, BHARATHIAR UNIVERSITY, COIMBATORE-641046 TAMILNADU
  • Selvaraj Mohana Roopan School of Advanced Sciences, VIT University, Vellore 632 014, Tamilnadu, India.

DOI:

https://doi.org/10.1007/2068

Ключевые слова:

2-chloroquinoline-3-carbaldehyde, 2, 6-dichloroquinolin-4-amine, N-(quinolin-4-yl)-2-oxo-1, 2-dihydroquinoline-3-carboxamide, benzo[b]quino[4, 3-h][1, 6]naphthyridin-6(5H)-one

Аннотация

The reaction of 2-oxo-1,2-dihydroquinoline-3-carbonyl chlorides and 2,6-dichloroquinolin-4-amine leads to the formation of N-(2,6-dichloroquinolin-4-yl)-2-oxo-1,2-dihydroquinoline-3-carboxamides. The latter is cyclized to fused [1,6]naphthyridine derivative – 3,13-dichlorobenzo[b]quino[4,3-h][1,6]naphthyridin-6(5H)-one, under heating in polyphosphoric acid at 150°C. The reaction sequence was generalized and was extended to synthetic derivatives. The structures of all synthesized compounds were confirmed by spectral data and elemental analysis.

How to Cite
Magesh Selva Kumar, A. K. M.; Rajendran, S. P.; Mohana Roopan, S. Chem. Heterocycl. Compd. 2015, 51, 346. [Khim. Geterotsikl. Soedin. 2015, 51, 346.]

For this article in the English edition see DOI 10.1007/s10593-015-1706-5

 

Биографии авторов

Adhiyaman Kottai Munusamy Magesh Selva Kumar, DEPARTMENT OF CHEMISTRY, BHARATHIAR UNIVERSITY, COIMBATORE-641046 TAMILNADU

Research Scholar in Department of chemistry

Subramanian Parameswaran Rajendran, DEPARTMENT OF CHEMISTRY, BHARATHIAR UNIVERSITY, COIMBATORE-641046 TAMILNADU

Professor (Rtd) in Department of Chemistry

Selvaraj Mohana Roopan, School of Advanced Sciences, VIT University, Vellore 632 014, Tamilnadu, India.

Assistant Professor in VIT University

Опубликован

2015-04-27

Выпуск

Раздел

Оригинальные статьи