CONDENSED ISOQUINOLINES. 27. SYNTHESIS AND OXIDATION REACTIONS OF 5,13-DIHYDRO-11H-ISOQUINO[3,2-<i>b</i>]QUINAZOLIN-11-ONE

Authors

  • Л. М. Потиха Taras Shevchenko Kiev National University, Kiev 01033
  • Р. М. Гуцул Taras Shevchenko Kiev National University, Kiev 01033
  • А. В. Туров Taras Shevchenko Kiev National University, Kiev 01033
  • В. А. Ковтуненко Taras Shevchenko Kiev National University, Kiev 01033

DOI:

https://doi.org/10.1007/6984

Keywords:

2-aminobenzylamine, [6, 6′]bi[isoquino[3, 2-b]quinazoline], dibenzo[b, f][1, 8]naphthyridine, isoquino[3, 2-b]quinazoline, 2-(cyanomethyl)benzoic acid, oxidation, rearrangement

Abstract

Condensation of 2-(cyanomethyl)benzoic acid with 2-aminobenzylamine gave 6,11-dihydro-13H-isoquino[3,2-b]quinazolin-11-one. Its oxidation in  nitrobenzene led to the formation of 5,13,5′,13′-hexahydro[6,6′]bi[isoquino[3,2-b]quinazoline]-11,11′-dione, but in dichlorobenzene in the presence of elemental sulfur and iodine it gave the rearrangement product 6H-dibenzo[b,f][1,8]naphthyridin-5-one.

How to Cite
Potikha, L. M.; Gutsul, R. M.; Turov, A. V.; Kovtunenko, V. A.  Chem. Heterocycl. Compd. 2008, 44, 208. [Khim. Geterotsikl. Soedin. 2008, 273.]

For this article in the English edition see DOI 10.1007/s10593-008-0024-6

 

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Published

2022-08-15

Issue

No. 2 (2008)

Section

Original Papers