REACTION OF 1,2,3,4-TETRAHYDROISOQUINOLINE ENAMINES WITH QUINONES

Authors

  • Н. Н. Полыгалова Perm State Pharmaceutical Academy, 614990 Perm
  • А. Г. Михайловский Perm State Pharmaceutical Academy, 614990 Perm
  • М. И. Вахрин Perm State Pharmaceutical Academy, 614990 Perm

DOI:

https://doi.org/10.1007/7791

Keywords:

benzo[g]naphtho[2, 3-b]indolyzine-8, 13-diones, p-benzoquinone, 2, 3-dichloro-1, 4-naphthoquinone, indolo[2, 1-a]isoquinoline, 1, 3, 4-tetrahydroisoquinoline enamines, donor–acceptor complexes, Michael addition, Nenicescu reaction

Abstract

The reaction of p-benzoquinone with enamino  amides derived from 2,2-dimethyl-1,2,3,4-tetrahydrobenzo[f]isoquinoline proceeds through a Michael addition. The reaction of this quinone with the base of drotaverine leads to a derivative of indolo[2,1-a]isoquinoline. Fusion of isoquinoline enamines by the action of 2,3-dichloro-1,4-naphthoquinone leads to pentacyclic benzo[g]naphtho-[2,3-b]indolyzine-8,13-dione.

How to Cite
Polygalova, N. N.; Mikhailovskii, A. G.; Vakhrin, M. I.  Chem. Heterocycl. Compd. 2006, 42, 1352. [Khim. Geterotsikl. Soedin. 2006, 1565.]

For this article in the English edition see DOI 10.1007/s10593-006-0248-2


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Published

2023-05-16

Issue

No. 10 (2006)

Section

Original Papers