4-HYDROXY-2-QUINOLONES. 107. REACTION OF TRIETHYL METHANETRICARBOXYLATE WITH INDOLINE

Authors

  • И. В. Украинец National Pharmaceutical University, Kharkiv 61002
  • О. В. Горохова National Pharmaceutical University, Kharkiv 61002
  • Л. В. Сидоренко National Pharmaceutical University, Kharkiv 61002
  • Н. Л. Березнякова National Pharmaceutical University, Kharkiv 61002

DOI:

https://doi.org/10.1007/7841

Keywords:

amides of 4-hydroxy-2-oxo-1, 2-dihydroquinoline-3-carboxylic acids, heterocyclic derivatives of tricarbonylmethane, ethyl esters, X-ray structural analysis, thermolysis

Abstract

The first stage of the reaction of triethyl methanetricarboxylate with indoline is the formation of the diethyl ester of 2-(indoline-1-carbonyl)malonic acid, which then, depending on the conditions selected, may be converted into the ethyl ester of 2-(indoline-1-carbonyl)-3-(indolin-1-yl)-3-oxopropionic acid, methanetri-N-(indolin-1-yl)carboxamide, or the ethyl ester or (indolin-1-yl)amide of 1-hydroxy-3-oxo-5,6-dihydro-3H-pyrrolo[3,2,1-ij]quinoline-2-carboxylic acid.

How to Cite
Ukrainets, I. V.; Gorokhova, O. V.; Sidorenko, L. V.; Bereznyakova, N. L.  Chem. Heterocycl. Compd. 2006, 42, 1032. [Khim. Geterotsikl. Soedin. 2006, 1191.]

For this article in the English edition see DOI 10.1007/s10593-006-0200-5


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Published

2023-05-26

Issue

No. 8 (2006)

Section

Original Papers