SYNTHESIS AND REACTIVITY OF α-BROMO-4-(DIFLUOROMETHYLTHIO)ACETOPHENONE

Authors

  • А. М. Демченко T. G. Shevchenko Chernigov Pedagogical University, Chernigov 14038
  • К. Г. Назаренко Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kiev 02094
  • А. П. Андрушко T. G. Shevchenko Chernigov Pedagogical University, Chernigov 14038
  • Д. В. Федюк Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kiev 02094
  • А. Н. Красовский T. G. Shevchenko Chernigov Pedagogical University, Chernigov 14038
  • Л. М. Ягупольский Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kiev 02094

Keywords:

α-bromo-4-difluoromethylthioacetophenone, Freon-22 (CHF2Cl), SCHF2 group, difluoromethylation method

Abstract

A synthesis is reported for α-bromo-4-difluoromethylthioacetophenone and the conditions for the condensation of this compound with 2-aminothiazole, 2-amino-5-chloropyridine, 2-amino-4,5-dihydro-3H-pyrrole, benzimidazoline-2-thione, oxadiazoline-2-thione, and thiourea were studied. S- and N-substituted azaheterocycles containing the 4-(difluoromethylthio)phenyl fragment were synthesized and characterized.

How to Cite
Demchenko, A. M.; Nazarenko, K. G.; Andrushko, A. P.; Fediyuk, D. V.; Krasovsky, A. N.; Yagupolsky, L. M. Chem. Heterocycl. Compd. 2003, 39, 965. [Khim. Geterotsikl. Soedin. 2003, 1109.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1026114908997

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Published

2003-07-25

Issue

No. 7 (2003)

Section

Original Papers