ADENINE AND URACIL DERIVATIVES WITH ANTITUBERCULAR ACTIVITY

Authors

  • Э. Алкснис Latvian Institute of Organic Synthesis, Riga LV-1006
  • Д. Корнеева Latvian Institute of Organic Synthesis, Riga LV-1006
  • Э. Лукевиц Latvian Institute of Organic Synthesis, Riga LV-1006

Keywords:

pyrimidines, purines, alkylation, tuberculosis

Abstract

We have carried out the synthesis and investigated the antitubercular activity of adenine and 5‑fluorouracil derivatives. It was found that a comparatively large, lipophilic fragment is needed in the active molecule to inhibit the tuberculosis pathogen.

How to Cite
Alksnis, E.; Korneeva, D.; Lukevics, E Chem. Heterocycl. Compd. 2001, 37, 743. [Khim. Geterotsikl. Soedin. 2001, 807.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1011973514672

Downloads

Published

2001-06-25

Issue

No. 6 (2001)

Section

Original Papers