7-ARYL-4a-HYDROXY-4a,6,7,7a-TETRAHYDROISOXAZOLO[4,5-<i>b</i>]QUINUCLIDINES AS NO DONORS

Authors

  • Л. H. Койков Center for the Chemistry of Medicinal Substances, All Russia Science Research Chemico-Pharmaceutical Institute, Moscow 119815
  • H. B. Алексеева Russian Federation State Science Center, Science Research Institute for Intermediate Products and Dyes, Moscow 103787
  • Н. Б. Григорьев Center for the Chemistry of Medicinal Substances, All Russia Science Research Chemico-Pharmaceutical Institute, Moscow 119815
  • B. И. Левина Center for the Chemistry of Medicinal Substances, All Russia Science Research Chemico-Pharmaceutical Institute, Moscow 119815
  • K. Ф. Тypчин Center for the Chemistry of Medicinal Substances, All Russia Science Research Chemico-Pharmaceutical Institute, Moscow 119815
  • Т. Я. Филипенко Center for the Chemistry of Medicinal Substances, All Russia Science Research Chemico-Pharmaceutical Institute, Moscow 119815
  • В. Г. Граник Russian Federation State Science Center, Science Research Institute for Intermediate Products and Dyes, Moscow 103787

Keywords:

arylmethylene quinuclidine, hydroxylamine, NO donors, quinuclidone oxime, hydrogenation

Abstract

7-Aryl-4a-hydroxy-4a,6,7,7a-tetrahydroisoxazolo[4,5-b]quinuclidines have been prepared from 2‑arylmethylene-3-quinuclidones and hydroxylamine and they are able to release NO upon mild oxidation with K3[Fe(CN6)] in basic medium.

How to Cite
Koikov, L. N.; Alekseeva, N. V.; Grigor'ev, N. B.; Levina, V. I.; Turchin, K. F.; Filipenko, T. Ya.; Granik, V. G. Chem. Heterocycl. Compd. 2001, 37, 620. [Khim. Geterotsikl. Soedin. 2001, 673.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1011616924260

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Published

2001-05-25

Issue

No. 5 (2001)

Section

Original Papers