A CONVENIENT ROUTE TO CYANO DERIVATIVES OF BENZONAPHTHYRIDINES

Авторы

  • B. Bachowska Institute of Chemistry, Environmental Protection, and Biotechnology, Jan Długosz University

DOI:

https://doi.org/10.1007/2106

Ключевые слова:

benzonaphthyridine N-oxides, carbonitriles, carboxylic acids, cyanation

Аннотация

A smooth synthesis of benzo[c][1,5]naphtyridine-6-carbonitrile and benzo[h][1,6]naphthyridine-5-carbonitrile, starting from benzonaphthyridine N-oxides, is achieved by treatment with trimethylsilane carbonitrile (Me3SiCN) in CH2Cl2 at 0–5°C. The resulting nitriles are then hydrolyzed to corresponding acids by boiling in aqueous alkali.

How to Cite
Bachowska, B. Chem. Heterocycl. Compd. 2011, 47(3), 332. [Khim. Geterotsikl. Soedin. 2011, 406.]

For this article in the English edition see DOI 10.1007/s10593-011-0761-9

Загрузки

Опубликован

2014-12-01

Выпуск

№ 3 (2011)

Раздел

Оригинальные статьи